BeschreibungThree of our five senses, namely, seeing, hearing, and touching, have been commercialized in small powerful sensors and are ubiquitous in our everyday life (smartphone etc). Odor and taste, due to their fundamentally different detection mechanism, represent an extreme challenge for the technical implementation. In contrast to readily available devices that mimic mechano- or photoreceptors, which enable powerful optical and tactile sensors, artificial chemoreceptors are needed for the realization of smell and taste. These chemoreceptors are capable of translating a chemical-biological signal into an electronic one and are a prerequisite for odor and taste sensors. In this presentation we will highlight our research efforts using three different biomimetic approaches: A) low-cost polymer-based sensors that mimic our combinatorial code for IoT applications, B) protein engineering of natural odorant binding proteins to increase and tune specificity C) tethered lipid membranes to mimic the cell membrane and allow for hosting olfactory receptors. Finally, we also present our novel combined SPR/EG-FET sensor platform. By combining surface plasmon resonance (SPR) and electrolyte gated field-effect transistor (EG-FET) methods in a single analytical device we introduce a novel tool for surface investigations, enabling simultaneous measurements of the surface mass and charge density changes in real-time. This is realized by using a gold sensor surface that simultaneously serves as gate-electrode of the EG-FET and as SPR active interface. These simultaneous label-free and real-time measurements allow new insights into complex processes at the solid liquid interface, which are beyond the scope of each individual tool. The aim of our research is to produce, characterize, compare and benchmark biomimetic smell sensors using various sensing principles to create a better understanding of the olfactory process.
|17 Aug. 2020 → 20 Aug. 2020
|ACS Fall 2020 Virtual Meeting & Expo
- Biosensor Technologies