Bio-nanoengineering to detect and antagonize multidrug-resistant pathogens

Publikation: AbschlussarbeitHabilitation


The emerging field of bio-nanoengineering provides us with novel tools to exploit biological mechanisms and machineries and allows us to engineer complex molecular systems for a manifold of applications. An important application area concerns infectious diseases that are still a major threat to our health and one of the leading causes of death. In this thesis, established and new diagnostic technologies to characterise pathogens and antibiotic resistances will be presented. A special focus will be put on high-multiplex technologies. The versatility of DNA and its use as a biomarker, enzyme, target-binding molecule, and building material is discussed. Aptamers and DNA origami are especially fascinating examples for DNA-based tools. The modelling of complex molecular systems requires a diverse set of in silico tools and is also presented in this thesis
Gradverleihende Hochschule
  • TU Wien
Betreuer/-in / Berater/-in
  • Mach, Robert, Betreuer:in, Externe Person
Datum der Bewilligung28 Aug. 2023
PublikationsstatusVeröffentlicht - 28 Aug. 2023

Research Field

  • Molecular Diagnostics


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