Poly(ADP-Ribose)Synthese und Regulationsstörungen bei Erkrankungen

H. Altmann

    Publikation: Beitrag in FachzeitschriftArtikel


    Poly(ADP-ribose) is a polyanion involved in the regulation of the DNA metabolism of cells. DNA repair, semiconservative DNA- synthesis, differentiation- and transformation functions are connected to changes in the activity of the poly(ADP-ribose)- polymerase. The incidence of most cancers shows a steady increase with age while the PAR-synthesis decreases linear in certain cells with age. In some diseases abnormalities could be detected in PAR-synthesis and binding to nuclear proteins. (Author)
    Seiten (von - bis)861-864
    FachzeitschriftWien. Klin. Wochenschr.(Dec 1983)
    PublikationsstatusVeröffentlicht - 1983

    Research Field

    • Nicht definiert


    • FZS-000BLP

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