Polydopamine Meets Solid-State Nanopores: A Bioinspired Integrative Surface Chemistry Approach To Tailor the Functional Properties of Nanofluidic Diodes

The ability to modulate the surface chemical characteristics of solid-state nanopores is of great interest as it provides the means to control the macroscopic response of nanofluidic devices. For instance, controlling surface charge and polarity of the pore walls is one of the most important applications of surface modification that is very relevant to attain an accurate control over the transport of ions through the nanofluidic architecture. In this work, we describe a new integrative chemical approach to fabricate nanofluidic diodes based on the self-polymerization of dopamine (PDOPA) on asymmetric track-etched nanopores. Our results demonstrate that PDOPA coating is not only a simple and effective method to modify the inner surface of polymer nanopores fully compatible with the fabrication of nanofluidic devices but also a versatile platform for further integration of more complex molecules through different covalent chemistries and self-assembly processes. We adjusted the chemical modification strategy to obtain various configurations of the pore surface: (i) PDOPA layer was used as primer, precursor or even responsive functional coating, (ii) PDOPA layer was used as a platform for anchoring chemical functions via the Michael addition reaction, and (iii) PDOPA was used as a reactive layer inducing the metallization of the pore walls through the in-situ reduction of metallic precursors present in solution. We believe that the transversal concept of integrative surface chemistry offered by polydopamine in combination with the remarkable physical characteristics of asymmetric nanopores constitutes a new framework to design multifunctional nanofluidic devices employing soft chemistry-based nanofunctionalization techniques. Figures in this publication Figure 2. (A) Scheme showing the formation of the PDOPA layer on the... Figure 3. (a) Chemical equilibrium associated with the pH-dependent... Figure 4. (A) Scheme showing the covalent grafting of 3-amino-... Figure 5. (A) Scheme describing the nanochannel metallization process... Get notified about updates to this publication Follow publication Download full-text Full-text Available from: Omar Azzaroni, Aug 03, 2015 Share Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable. References (51) Cited In (7) Source Article: Catecholamine coated maghemite nanoparticles for the environmental remediation: Hexavalent chromium ions removal Ali Nematollahzadeh · Somaye Seraj · Behruz Mirzayi [Show abstract] Full-text · Article · Apr 2015 · The Chemical Engineering Journal Download Article: Engineered Ionic Gates for Ion Conduction Based on Sodium and Potassium Activated Nanochannels Qian Liu · Kai Xiao · Liping Wen · Heng Lu · Yahui Liu · Xiang-Yu Kong · Ganhua Xie · Zhen Zhang · Zhishan Bo · Lei Jiang [Show abstract] No preview · Article · Sep 2015 · Journal of the American Chemical Society Request full-text Source Article: Host-guest supramolecular chemistry in solid-state nanopores: potassium-driven modulation of ionic transport in nanofluidic diodes Gonzalo Pérez-Mitta · Alberto G Albesa · Wolfgang Knoll · Christina Trautmann · María Eugenia Toimil-Molares · Omar Azzaroni [Show abstract] Full-text · Article · Sep 2015 · Nanoscale Download Show more Note: This list is based on the publications in our database and might not be exhaustive. Similar Publications Surface Reactivity of YSZ, Y 2 O 3 and ZrO 2 Towards CO, CO 2 and CH 4 : A Comparative Discussion Michaela Kogler, Eva-Maria Köck, Bernhard Klötzer, Lukas Perfler, Simon Penner Surface Modification of Intraocular Lenses Qi Huang, GeorgePak-Man Cheng, Kin Chiu, Gui-Qin Wang Thiol-Maleimide Michael Addition Click Reaction: A New Route to Surface Modification of Porous Polymeric Monolith Sabrina Belbekhouche, Mohamed Guerrouache, Benjamin Carbonnier © 2008‐2016 researchgate.net. All rights reserved. About us · Contact us · Careers · Developers · News · Help Center · Privacy · Terms | Advertising · Recruiting We use cookies to give you the best possible experience on ResearchGate. Read our cookies policy to learn more. Ok Join for free Log in ResearchGate is the professional network for scientists and researchers. The ability to modulate the surface chemical characteristics of solid-state nanopores is of great interest as it provides the means to control the macroscopic response of nanofluidic devices. For instance, controlling surface charge and polarity of the pore walls is one of the most important applications of surface modification that is very relevant to attain an accurate control over the transport of ions through the nanofluidic architecture. In this work, we describe a new integrative chemical approach to fabricate nanofluidic diodes based on the self-polymerization of dopamine (PDOPA) on asymmetric track-etched nanopores. Our results demonstrate that PDOPA coating is not only a simple and effective method to modify the inner surface of polymer nanopores fully compatible with the fabrication of nanofluidic devices but also a versatile platform for further integration of more complex molecules through different covalent chemistries and self-assembly processes. We adjusted the chemical modification strategy to obtain various configurations of the pore surface: (i) PDOPA layer was used as primer, precursor or even responsive functional coating, (ii) PDOPA layer was used as a platform for anchoring chemical functions via the Michael addition reaction, and (iii) PDOPA was used as a reactive layer inducing the metallization of the pore walls through the in-situ reduction of metallic precursors present in solution. We believe that the transversal concept of integrative surface chemistry offered by polydopamine in combination with the remarkable physical characteristics of asymmetric nanopores constitutes a new framework to design multifunctional nanofluidic devices employing soft chemistry-based nanofunctionalization techniques. Figures in this publication Figure 2. (A) Scheme showing the formation of the PDOPA layer on the... Figure 3. (a) Chemical equilibrium associated with the pH-dependent... Figure 4. (A) Scheme showing the covalent grafting of 3-amino-... Figure 5. (A) Scheme describing the nanochannel metallization process... Get notified about updates to this publication Follow publication Download full-text Full-text Available from: Omar Azzaroni, Aug 03, 2015 Share Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. The impact factor represents a rough estimation of the journal's impact factor and does not reflect the actual current impact factor. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable. References (51) Cited In (7) Source Article: Catecholamine coated maghemite nanoparticles for the environmental remediation: Hexavalent chromium ions removal Ali Nematollahzadeh · Somaye Seraj · Behruz Mirzayi [Show abstract] Full-text · Article · Apr 2015 · The Chemical Engineering Journal Download Article: Engineered Ionic Gates for Ion Conduction Based on Sodium and Potassium Activated Nanochannels Qian Liu · Kai Xiao · Liping Wen · Heng Lu · Yahui Liu · Xiang-Yu Kong · Ganhua Xie · Zhen Zhang · Zhishan Bo · Lei Jiang [Show abstract] No preview · Article · Sep 2015 · Journal of the American Chemical Society Request full-text Source Article: Host-guest supramolecular chemistry in solid-state nanopores: potassium-driven modulation of ionic transport in nanofluidic diodes Gonzalo Pérez-Mitta · Alberto G Albesa · Wolfgang Knoll · Christina Trautmann · María Eugenia Toimil-Molares · Omar Azzaroni [Show abstract] Full-text · Article · Sep 2015 · Nanoscale Download Show more Note: This list is based on the publications in our database and might not be exhaustive. Similar Publications Surface Reactivity of YSZ, Y 2 O 3 and ZrO 2 Towards CO, CO 2 and CH 4 : A Comparative Discussion Michaela Kogler, Eva-Maria Köck, Bernhard Klötzer, Lukas Perfler, Simon Penner Surface Modification of Intraocular Lenses Qi Huang, GeorgePak-Man Cheng, Kin Chiu, Gui-Qin Wang Thiol-Maleimide Michael Addition Click Reaction: A New Route to Surface Modification of Porous Polymeric Monolith Sabrina Belbekhouche, Mohamed Guerrouache, Benjamin Carbonnier © 2008‐2016 researchgate.net. All rights reserved. About us · Contact us · Careers · Developers · News · Help Center · Privacy · Terms | Advertising · Recruiting We use cookies to give you the best possible experience on ResearchGate. Read our cookies policy to learn more. Ok Join for free Log in The ability to modulate the surface chemical characteristics of solid-state nanopores is of great interest as it provides the means to control the macroscopic response of nanofluidic devices. For instance, controlling surface charge and polarity of the pore walls is one of the most important applications of surface modification that is very relevant to attain an accurate control over the transport of ions through the nanofluidic architecture. In this work, we describe a new integrative chemical approach to fabricate nanofluidic diodes based on the self-polymerization of dopamine (PDOPA) on asymmetric track-etched nanopores. Our results demonstrate that PDOPA coating is not only a simple and effective method to modify the inner surface of polymer nanopores fully compatible with the fabrication of nanofluidic devices but also a versatile platform for further integration of more complex molecules through different covalent chemistries and self-assembly processes. We adjusted the chemical modification strategy to obtain various configurations of the pore surface: (i) PDOPA layer was used as primer, precursor or even responsive functional coating, (ii) PDOPA layer was used as a platform for anchoring chemical functions via the Michael addition reaction, and (iii) PDOPA was used as a reactive layer inducing the metallization of the pore walls through the in-situ reduction of metallic precursors present in solution. We believe that the transversal concept of integrative surface chemistry offered by polydopamine in combination with the remarkable physical characteristics of asymmetric nanopores constitutes a new framework to design multifunctional nanofluidic devices employing soft chemistry-based nanofunctionalization techniques.