Recent advances and future applications of microfluidic live-cell microarrays

Mario Rothbauer, David Wartmann, Verena Charwat, Peter Ertl

    Publikation: Beitrag in FachzeitschriftArtikelBegutachtung

    Abstract

    Microfluidic live-cell microarrays show much promise as screening tools for biomedical research because they could shed light on key biological processes such as cell signaling and cell-to-cell and cell-to-substrate dynamic responses. While miniaturization reduces the need for expensive clinical grade reagents, the integration of functional components including micropumps, biosensors, actuators, mixers and gradient generators results in improved assay reliability, reproducibility and well-defined cell culture conditions. The present review addresses recent technological advances in microfluidic live-cell microarray technology with a special focus on the applications of microfluidic single-cell, multi-cell and 3D cell microarrays.
    OriginalspracheEnglisch
    Seiten (von - bis)1
    Seitenumfang14
    FachzeitschriftBiotechnology Advances
    PublikationsstatusVeröffentlicht - 2015

    Research Field

    • Biosensor Technologies

    Schlagwörter

    • Microfluidics;

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