Retinal thermal damage threshold studies in the near-IR and for multiple pulses

Karl Schulmeister (Vortragende:r), Bernhard Seiser, Florian Edthofer, Johannes Husinsky, Letizia Farmer

Publikation: Beitrag in Buch oder TagungsbandVortrag mit Beitrag in TagungsbandBegutachtung

Abstract

multiple pulse exposures for the laser wavelength of 532 nm. The thresholds as determined by fluorescence viability staining compare very well with the prediction of thermal damage computer model that is based on the Arrhenius damage integral. Comparison of the experimental data with the thermal damage computer model that additivity of multiple pulses can be understood on the basis of partial thermal damage induced by the individual pulses. Both models were previously (BIOS 2006) validated against non-human primate threshold data. The multiple pulse thresholds for a given series of pulses were compared against the MPE evaluation method for multiple pulses, referred to as N-1/4 or Total on Time (TOT) rule. Variation of the pulse duration, retinal spot size and the spacing between pulses shows that the TOT rule either reflects the damage threshold trend for multiple pulses very well or errs on the conservative side.
OriginalspracheEnglisch
TitelOphthalmic Technologies XVII
Seitenumfang8
PublikationsstatusVeröffentlicht - 2007
VeranstaltungSPIE Conference on Laser and Noncoherent Light Ocular Effects -
Dauer: 1 Jan. 2007 → …

Konferenz

KonferenzSPIE Conference on Laser and Noncoherent Light Ocular Effects
Zeitraum1/01/07 → …

Research Field

  • Biosensor Technologies

Schlagwörter

  • laser safety
  • hazard analysis
  • computer model
  • bovine model
  • multiple pulse
  • retinal thermal injury
  • MPE
  • IEC 60825-1
  • ANSI Z136.1

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