Abstract
multiple pulse exposures for the laser wavelength of 532 nm. The thresholds as determined by fluorescence viability
staining compare very well with the prediction of thermal damage computer model that is based on the Arrhenius
damage integral. Comparison of the experimental data with the thermal damage computer model that additivity of
multiple pulses can be understood on the basis of partial thermal damage induced by the individual pulses. Both models
were previously (BIOS 2006) validated against non-human primate threshold data. The multiple pulse thresholds for a
given series of pulses were compared against the MPE evaluation method for multiple pulses, referred to as N-1/4 or
Total on Time (TOT) rule. Variation of the pulse duration, retinal spot size and the spacing between pulses shows that
the TOT rule either reflects the damage threshold trend for multiple pulses very well or errs on the conservative side.
Originalsprache | Englisch |
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Titel | Ophthalmic Technologies XVII |
Seitenumfang | 8 |
Publikationsstatus | Veröffentlicht - 2007 |
Veranstaltung | SPIE Conference on Laser and Noncoherent Light Ocular Effects - Dauer: 1 Jan. 2007 → … |
Konferenz
Konferenz | SPIE Conference on Laser and Noncoherent Light Ocular Effects |
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Zeitraum | 1/01/07 → … |
Research Field
- Biosensor Technologies
Schlagwörter
- laser safety
- hazard analysis
- computer model
- bovine model
- multiple pulse
- retinal thermal injury
- MPE
- IEC 60825-1
- ANSI Z136.1