Description
The application of advanced materials in the field of electrochemical biosensors is attracting increasing interest. At AIT, the development of these biosensor systems is focused on their application in minimally invasive medical diagnostics at the point-of-care (POC). The unique challenges associated with this field, such as the need for cost-effective production, sustainability of disposable devices, rapid diagnostics, low target analyte concentrations, and ease of use, necessitate the development of effective solutions.In addressing these challenges, the utilization of advanced materials is crucial, allowing the introduction of additional functionalities to biosensors or microfluidic systems.
AIT has developed a variety of advanced materials, including but not limited to nanoparticles [1], composites [2], redox-active materials [3], and hydrogels [3] (see Fig.1).
These materials have been tailored to improve the nanostructure of working electrodes [1], to be developed as nanozymes [4], to refine the electrodes, to increase sustainability, to enable label-free assays, to embed bioreagents in microfluidics, introduce molecular filter system, to increase the durability of reagents or to design biocompatible surfaces.
The presentation will show examples of the aforementioned materials and their respective areas of applications in POC systems, such as cancer diagnostics [1], pathogen detection, immunoassays, or metabolite detection on microneedle sensors for wearables [5,6].
Additionally, an overview on the production of modified sensor structures through automated surface modification will be given. This automated surface modification technique ensures high reproducibility; however, it necessitates the development of advanced materials, in form of inks or bioinks, tailored to be processed using dispensers or inkjet printer techniques.
References: Figure 1: Graphical Abstract
[1] V. Thoeny, E. Melnik, et al., Electrochimica Acta, 2023, 455, DOI: 10.1016/j.electacta.2023.142336.
[2] E. Melnik, V. Thoeny, et al., 2022, IEEE, DOI: 10.1109/FLEPS53764.2022.9781500.
[3] E. Melnik, S. Kurzhals, et al. Sensors, 2024, 24, DOI: 10.3390/s24113678.
[4] S. Kurzhals, E. Melnik, et al., Proceedings EUROSENSORS XXXVI, 2024, pp. 425–426, DOI: 10.5162/EUROSENSORSXXXVI/PT6.32.
[5] E. Cihan, E. Melnik, et al., Chemosensors, 2024, 12, 36, DOI: 10.3390/chemosensors12030036.
[6] A. Bocchino, C. Marquez-Grana, O. P. Singh, E. Melnik, et al., Sensors and Actuators A: Physical, 2025, 388, 116491, DOI: 10.1016/j.sna.2025.116491.
| Period | 25 Apr 2025 |
|---|---|
| Event title | 3rd International Conference on "Recent Trends on Prospective Applications of Advanced Materials-2025 (RTPAAM-2025) |
| Event type | Conference |
| Location | IndiaShow on map |
| Degree of Recognition | International |
Research Field
- Molecular Diagnostics