Complete inhibition of ABCB1 and ABCG2 at the blood-brain barrier by co-infusion of erlotinib and tariquidar to improve brain delivery of the model ABCB1/ABCG2 substrate [C-11]erlotinib

Nicolas Tournier; Sebastian Goutal; Severin Mairinger; Irene Hernandez Lozano; Thomas Filip; Michael Sauberer; Fabien Caille; L Breuil; Johann Stanek; A F Freeman; G Novarino; C Truillet; Thomas Wanek; Oliver Langer

doi:10.1177/0271678X20965500

Complete inhibition of ABCB1 and ABCG2 at the blood-brain barrier by co-infusion of erlotinib and tariquidar to improve brain delivery of the model ABCB1/ABCG2 substrate [C-11]erlotinib

Nicolas Tournier, Sebastian Goutal, Severin Mairinger, Irene Hernandez Lozano, Thomas Filip, Michael Sauberer, Fabien Caille, L Breuil, Johann Stanek, A F Freeman, G Novarino, C Truillet, Thomas Wanek, Oliver Langer

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	1634-1646
Number of pages	13
Journal	Journal of Cerebral Blood Flow and Metabolism
Volume	47
Issue number	7
DOIs	https://doi.org/10.1177/0271678X20965500
Publication status	Published - 2021

Research Field

Former Research Field - Health and Bioresources

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10.1177/0271678X20965500Licence: Unspecified

Cite this

Tournier, N., Goutal, S., Mairinger, S., Hernandez Lozano, I., Filip, T., Sauberer, M., Caille, F., Breuil, L., Stanek, J., Freeman, A. F., Novarino, G., Truillet, C., Wanek, T., & Langer, O. (2021). Complete inhibition of ABCB1 and ABCG2 at the blood-brain barrier by co-infusion of erlotinib and tariquidar to improve brain delivery of the model ABCB1/ABCG2 substrate [C-11]erlotinib. Journal of Cerebral Blood Flow and Metabolism, 47(7), 1634-1646. https://doi.org/10.1177/0271678X20965500

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title = "Complete inhibition of ABCB1 and ABCG2 at the blood-brain barrier by co-infusion of erlotinib and tariquidar to improve brain delivery of the model ABCB1/ABCG2 substrate [C-11]erlotinib",

author = "Nicolas Tournier and Sebastian Goutal and Severin Mairinger and {Hernandez Lozano}, Irene and Thomas Filip and Michael Sauberer and Fabien Caille and L Breuil and Johann Stanek and Freeman, {A F} and G Novarino and C Truillet and Thomas Wanek and Oliver Langer",

note = "iA GF/Kornelis, da Team Wanek 2021 auf KST LHRS",

year = "2021",

doi = "10.1177/0271678X20965500",

language = "English",

volume = "47",

pages = "1634--1646",

journal = "Journal of Cerebral Blood Flow and Metabolism",

issn = "0271-678X",

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Tournier, N, Goutal, S, Mairinger, S, Hernandez Lozano, I, Filip, T, Sauberer, M, Caille, F, Breuil, L, Stanek, J, Freeman, AF, Novarino, G, Truillet, C, Wanek, T & Langer, O 2021, 'Complete inhibition of ABCB1 and ABCG2 at the blood-brain barrier by co-infusion of erlotinib and tariquidar to improve brain delivery of the model ABCB1/ABCG2 substrate [C-11]erlotinib', Journal of Cerebral Blood Flow and Metabolism, vol. 47, no. 7, pp. 1634-1646. https://doi.org/10.1177/0271678X20965500

Complete inhibition of ABCB1 and ABCG2 at the blood-brain barrier by co-infusion of erlotinib and tariquidar to improve brain delivery of the model ABCB1/ABCG2 substrate [C-11]erlotinib. / Tournier, Nicolas; Goutal, Sebastian; Mairinger, Severin et al.
In: Journal of Cerebral Blood Flow and Metabolism, Vol. 47, No. 7, 2021, p. 1634-1646.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Complete inhibition of ABCB1 and ABCG2 at the blood-brain barrier by co-infusion of erlotinib and tariquidar to improve brain delivery of the model ABCB1/ABCG2 substrate [C-11]erlotinib

AU - Tournier, Nicolas

AU - Goutal, Sebastian

AU - Mairinger, Severin

AU - Hernandez Lozano, Irene

AU - Filip, Thomas

AU - Sauberer, Michael

AU - Caille, Fabien

AU - Breuil, L

AU - Stanek, Johann

AU - Freeman, A F

AU - Novarino, G

AU - Truillet, C

AU - Wanek, Thomas

AU - Langer, Oliver

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DO - 10.1177/0271678X20965500

M3 - Article

SN - 0271-678X

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SP - 1634

EP - 1646

JO - Journal of Cerebral Blood Flow and Metabolism

JF - Journal of Cerebral Blood Flow and Metabolism

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