Generation and validation of a humanized mouse model for studying the in vivo relevance of breast cancer resistance protein in tissue distribution and pharmacokinetics of drug candidates

Shannon Dallas; Laurent Salphati; David Gomez-Zepeda; Thomas Wanek; Liangfu Chen; Xiaoyan Chu; Jeevan Kunta; Mario Mezler; Marie-Claude Menet; Stephanie Chasseigneaux; Xavier Decleves; Oliver Langer; Esaie Pierre; Karen DiLoreto; Carolin Hoft; Loic Laplanche; Jodie Pang; Tony Pereira; Clara Andonian; Damir Simic; Anja Rode; Jocelyn Yabut; Xiaolin Zhang; Nico Scheer

Generation and validation of a humanized mouse model for studying the in vivo relevance of breast cancer resistance protein in tissue distribution and pharmacokinetics of drug candidates

Shannon Dallas
, Laurent Salphati
, David Gomez-Zepeda
, Thomas Wanek
, Liangfu Chen
, Xiaoyan Chu
, Jeevan Kunta
, Mario Mezler
, Marie-Claude Menet
, Stephanie Chasseigneaux
, Xavier Decleves
, Oliver Langer
, Esaie Pierre
, Karen DiLoreto
, Carolin Hoft
, Loic Laplanche
, Jodie Pang
, Tony Pereira
, Clara Andonian
, Damir Simic

Anja Rode, Jocelyn Yabut, Xiaolin Zhang, Nico Scheer

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	492-504
Number of pages	13
Journal	Molecular Pharmacology
Publication status	Published - 2016

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Research Field

Former Research Field - Health and Bioresources

Cite this

Dallas, S., Salphati, L., Gomez-Zepeda, D., Wanek, T., Chen, L., Chu, X., Kunta, J., Mezler, M., Menet, M.-C., Chasseigneaux, S., Decleves, X., Langer, O., Pierre, E., DiLoreto, K., Hoft, C., Laplanche, L., Pang, J., Pereira, T., Andonian, C., ... Scheer, N. (2016). Generation and validation of a humanized mouse model for studying the in vivo relevance of breast cancer resistance protein in tissue distribution and pharmacokinetics of drug candidates. Molecular Pharmacology, 492-504.

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title = "Generation and validation of a humanized mouse model for studying the in vivo relevance of breast cancer resistance protein in tissue distribution and pharmacokinetics of drug candidates",

author = "Shannon Dallas and Laurent Salphati and David Gomez-Zepeda and Thomas Wanek and Liangfu Chen and Xiaoyan Chu and Jeevan Kunta and Mario Mezler and Marie-Claude Menet and Stephanie Chasseigneaux and Xavier Decleves and Oliver Langer and Esaie Pierre and Karen DiLoreto and Carolin Hoft and Loic Laplanche and Jodie Pang and Tony Pereira and Clara Andonian and Damir Simic and Anja Rode and Jocelyn Yabut and Xiaolin Zhang and Nico Scheer",

year = "2016",

language = "English",

pages = "492--504",

journal = "Molecular Pharmacology",

issn = "0026-895X",

publisher = "Elsevier Inc.",

}

Dallas, S, Salphati, L, Gomez-Zepeda, D, Wanek, T, Chen, L, Chu, X, Kunta, J, Mezler, M, Menet, M-C, Chasseigneaux, S, Decleves, X, Langer, O, Pierre, E, DiLoreto, K, Hoft, C, Laplanche, L, Pang, J, Pereira, T, Andonian, C, Simic, D, Rode, A, Yabut, J, Zhang, X & Scheer, N 2016, 'Generation and validation of a humanized mouse model for studying the in vivo relevance of breast cancer resistance protein in tissue distribution and pharmacokinetics of drug candidates', Molecular Pharmacology, pp. 492-504.

TY - JOUR

T1 - Generation and validation of a humanized mouse model for studying the in vivo relevance of breast cancer resistance protein in tissue distribution and pharmacokinetics of drug candidates

AU - Dallas, Shannon

AU - Salphati, Laurent

AU - Gomez-Zepeda, David

AU - Wanek, Thomas

AU - Chen, Liangfu

AU - Chu, Xiaoyan

AU - Kunta, Jeevan

AU - Mezler, Mario

AU - Menet, Marie-Claude

AU - Chasseigneaux, Stephanie

AU - Decleves, Xavier

AU - Langer, Oliver

AU - Pierre, Esaie

AU - DiLoreto, Karen

AU - Hoft, Carolin

AU - Laplanche, Loic

AU - Pang, Jodie

AU - Pereira, Tony

AU - Andonian, Clara

AU - Simic, Damir

AU - Rode, Anja

AU - Yabut, Jocelyn

AU - Zhang, Xiaolin

AU - Scheer, Nico

PY - 2016

Y1 - 2016

M3 - Article

SN - 0026-895X

SP - 492

EP - 504

JO - Molecular Pharmacology

JF - Molecular Pharmacology

ER -