Abstract
Poly(ADP-ribose) is a polyanion involved in the regulation of the DNA metabolism of cells. DNA repair, semiconservative DNA- synthesis, differentiation- and transformation functions are connected to changes in the activity of the poly(ADP-ribose)- polymerase. The incidence of most cancers shows a steady increase with age while the PAR-synthesis decreases linear in certain cells with age. In some diseases abnormalities could be detected in PAR-synthesis and binding to nuclear proteins. (Author)
| Original language | German |
|---|---|
| Pages (from-to) | 861-864 |
| Number of pages | 4 |
| Journal | Wien. Klin. Wochenschr.(Dec 1983) |
| Publication status | Published - 1983 |
Research Field
- Not defined
Keywords
- FZS-000BLP